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Stock-Based Compensation - Summary of Stock-Based Compensation Expense (Details) - 2018 Equity Inducement Plan and 2016 Employee Stock Purchase Plan - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Employees      
Employee Service Share Based Compensation Allocation of Recognized Period Costs [Line Items]      
Total stock-based compensation expense $ 4,876 $ 4,046 $ 2,492
Non-Employees      
Employee Service Share Based Compensation Allocation of Recognized Period Costs [Line Items]      
Total stock-based compensation expense   234  
Research and Development | Employees      
Employee Service Share Based Compensation Allocation of Recognized Period Costs [Line Items]      
Total stock-based compensation expense 1,828 1,440 961
Research and Development | Non-Employees      
Employee Service Share Based Compensation Allocation of Recognized Period Costs [Line Items]      
Total stock-based compensation expense   234  
General and Administrative | Employees      
Employee Service Share Based Compensation Allocation of Recognized Period Costs [Line Items]      
Total stock-based compensation expense $ 3,048 $ 2,606 $ 1,531