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Stock-Based Compensation - Additional Information (Details) - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Feb. 20, 2018
Jan. 01, 2018
Jan. 01, 2017
2018 Equity Inducement Plan              
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]              
Initial reserves of common stock         1,100,000    
2016 Equity Incentive Plan              
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]              
Percentage of outstanding share of common stock     4.00%        
Additional number of shares available for issuance           666,807 537,233
Common stock available for future issuance 203,906   203,906        
2016 Equity Incentive Plan and 2018 Equity Inducement Plan | Stock Options              
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]              
Stock option to purchase an aggregate of common stock shares 203,600 244,100 1,033,100 1,016,900      
Stock options to purchase common stock aggregate fair value $ 1,500,000 $ 713,000 $ 5,400,000 $ 4,900,000      
2016 Employee Stock Purchase Plan              
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]              
Stock option to purchase an aggregate of common stock shares 0 0 30,937 18,184      
Aggregate cash proceeds from sale of shares     $ 78,000 $ 78,000