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Stock-Based Compensation - Summary of Stock-Based Compensation Expense (Details) - 2016 Employee Stock Purchase Plan - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Employee Service Share Based Compensation Allocation of Recognized Period Costs [Line Items]        
Total stock-based compensation expense $ 666 $ 389 $ 1,066 $ 529
Research and Development        
Employee Service Share Based Compensation Allocation of Recognized Period Costs [Line Items]        
Total stock-based compensation expense 285 156 395 210
General and Administrative        
Employee Service Share Based Compensation Allocation of Recognized Period Costs [Line Items]        
Total stock-based compensation expense $ 381 $ 233 $ 671 $ 319