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Share/Stock-Based Compensation - Summary of Weighted-Average Assumptions Used in Calculating Fair Value of Awards (Details)
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Employee Service Share Based Compensation Allocation of Recognized Period Costs [Line Items]    
Dividend yield 0.00%  
2016 Plan and 2015 Plan    
Employee Service Share Based Compensation Allocation of Recognized Period Costs [Line Items]    
Expected term 5 years 11 months 27 days 6 years 3 months 15 days
Expected volatility 87.00% 87.00%
Risk-free interest 1.28% 1.37%
Dividend yield 0.00% 0.00%
2016 Employee Stock Purchase Plan    
Employee Service Share Based Compensation Allocation of Recognized Period Costs [Line Items]    
Expected term 5 months 12 days  
Expected volatility 82.00%  
Risk-free interest 0.50%  
Dividend yield 0.00%