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Related Party Transactions - Additional Information (Details) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Dec. 31, 2015
Spouse Of Chief Executive Officer          
Related Party Transaction [Line Items]          
Outstanding liability to related party $ 11,000   $ 11,000   $ 129,000
Spouse Of Chief Executive Officer | Research and Development          
Related Party Transaction [Line Items]          
Consulting fees 65,000 $ 110,000 389,000 $ 332,000  
One Of The Founders          
Related Party Transaction [Line Items]          
Consulting fees 25,000 $ 14,000 50,000 $ 39,000  
Outstanding liability to related party $ 9,000   9,000   $ 0
Annual consulting fees to company founder     $ 50,000    
One Of The Founders | Stock Option          
Related Party Transaction [Line Items]          
Shares issued to related party converted into stock options     13,852    
One Of The Founders | Unvested Restricted Common Stock          
Related Party Transaction [Line Items]          
Shares issued to related party converted into restricted stock awards     43,290    
One Of The Founders | Common B Shares          
Related Party Transaction [Line Items]          
Shares issued to related party     57,142