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Stock-Based Compensation - Schedule of Estimate Fair Value of Stock Options Granted (Details)
3 Months Ended 6 Months Ended
Jun. 30, 2016
Jun. 30, 2015
Jun. 30, 2016
Jun. 30, 2015
2016 Plan and 2015 Plan        
Employee Service Share Based Compensation Allocation of Recognized Period Costs [Line Items]        
Expected term 6 years 6 years 3 months 15 days 6 years 6 years 3 months 15 days
Expected volatility 87.00% 87.00% 87.00% 87.00%
Risk-free interest 1.29% 1.37% 1.29% 1.37%
Dividend yield 0.00% 0.00% 0.00% 0.00%
2016 Employee Stock Purchase Plan        
Employee Service Share Based Compensation Allocation of Recognized Period Costs [Line Items]        
Expected term 4 months 10 days   4 months 10 days  
Expected volatility 85.00%   85.00%  
Risk-free interest 0.36%   0.36%  
Dividend yield 0.00%   0.00%