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Net Loss Per Share (Tables)
9 Months Ended 12 Months Ended
Sep. 30, 2023
Dec. 31, 2022
Earnings Per Share [Abstract]    
Weighted-Average Equity Instruments Excluded from Calculation of Diluted Net Loss Per Share
The following weighted-average equity instruments were excluded from the calculation of diluted net loss per share because their effect would have been anti-dilutive for the periods presented:
 
     Three Months Ended
September 30,
     Nine Months Ended
September 30,
 
     2023      2022      2023      2022  
Options to purchase common stock
     3,135,672        351,533        1,426,224        335,395  
Unvested restricted stock units
     —          6,000        252        7,315  
Series A Preferred Stock (on an
as-converted
basis)
     42,501,681        —          14,851,447        —    
The following weighted-average equity instruments were excluded from the calculation of diluted net loss per share because their effect would have been anti-dilutive for the periods presented:
 
    
Year Ended December 31,
 
    
2022
    
2021
    
2020
 
Options to purchase common stock
     346,331        264,858        201,977  
Unvested restricted stock units
     6,982        7,975        4,239  
Schedule of Reconciliation of Basic and Diluted Net Loss Per Share  
The following is a reconciliation of the shares used as the denominator for the calculation of basic and diluted net loss per share:
 
    
Year Ended December 31,
 
    
2022
    
2021
    
2020
 
Weighted average common shares
     2,307,668        1,956,933        1,608,952  
Weighted average
pre-funded
warrants
     1,063,563        672,851        525,917  
  
 
 
    
 
 
    
 
 
 
Total basic and diluted weighted average shares
     3,371,231        2,629,784        2,134,869