Income Taxes (Tables)

12 Months Ended

Dec. 31, 2022

Income Tax Disclosure [Abstract]

Schedule of Loss Income Before Income Tax Expense by Jurisdiction

The following table summarizes the (loss) income before income tax expense by jurisdiction for the periods indicated:

	Year Ended December 31,
	2022			2021			2020
Domestic	$	(84,113	)	$	(65,940	)	$	(80,893	)
Foreign		162			280			—
Loss before income tax expense	$	(83,951	)	$	(65,660	)	$	(80,893	)

Summary of Difference Between Provision for Income Taxes and Amounts Computed by Applying Statutory Federal Income Tax Rate to Income Before Income Taxes

The difference between the Company’s provision for income taxes and the amounts computed by applying the statutory federal income tax rate to income before income taxes is as follows (in thousands):

	Year Ended December 31,
	2022			2021			2020
Tax provision derived by applying the federal statutory rate to income before income taxes	$	(17,630	)	$	(13,789	)	$	(16,988	)
Permanent differences and other		1,042			1,002			482
Federal tax credits		(3,559	)		(3,815	)		(3,905	)
State tax credits		(640	)		(152	)		(251	)
Effect of tax rate on foreign jurisdiction		42			(5	)		—
Change in the valuation allowance		20,609			16,900			20,662
Income tax (benefit) expense	$	(136	)	$	141		$	—

Components of Deferred Tax Assets and Liabilities

The components of the deferred tax assets and liabilities consist of the following (in thousands):

	December 31,
	2022			2021
Deferred tax assets
Net operating loss carryforward	$	68,917		$	64,531
Intangible assets		11,149			57
Deferred revenue		566			—
Accrued expense		668			846
Stock-based compensation		3,293			2,767
Federal tax credits		21,914			18,579
State tax credits		1,631			991
Other		190			220
Total deferred tax assets		108,328			87,991
Deferred tax liabilities
Depreciable assets		(676	)		(948	)
Total deferred tax liabilities		(676	)		(948	)
Less: Valuation allowance		(107,652	)		(87,043	)
Deferred tax assets, net	$	—		$	—