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Restructuring Charges - Summary of Charges Related to the Restructuring Activities (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Jun. 30, 2023
Jun. 30, 2022
Restructuring Cost and Reserve [Line Items]        
Severance and related     $ 6,400  
Stock compensation $ 1,911 $ 2,018 3,620 $ 4,118
Loss on disposal of long lived assets     915  
Lease asset impairment     900  
Research and Development        
Restructuring Cost and Reserve [Line Items]        
Stock compensation 394 691 1,171 1,392
General and Administrative        
Restructuring Cost and Reserve [Line Items]        
Stock compensation $ 1,517 $ 1,327 2,449 $ 2,726
Restructuring Activities        
Restructuring Cost and Reserve [Line Items]        
Severance and related     6,448  
Stock compensation     993  
Loss on disposal of long lived assets     931  
Lease asset impairment     2,580  
Total Restructuring Costs     10,952  
Restructuring Activities | Research and Development        
Restructuring Cost and Reserve [Line Items]        
Severance and related     3,182  
Stock compensation     123  
Loss on disposal of long lived assets     749  
Lease asset impairment     1,405  
Total Restructuring Costs     5,459  
Restructuring Activities | General and Administrative        
Restructuring Cost and Reserve [Line Items]        
Severance and related     3,266  
Stock compensation     870  
Loss on disposal of long lived assets     182  
Lease asset impairment     1,175  
Total Restructuring Costs     $ 5,493