Asset Acquisition - Schedule of Asset Acquisition Cost (Details) - USD ($) $ in Thousands		3 Months Ended		6 Months Ended
	Jun. 22, 2023	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022
Asset Acquisition [Line Items]
Assumed liabilities	$ 20,200
Transaction costs incurred by Aeglea	3,200
Fair value of Parapyre Options assumed by Aeglea	100
Acquired in-process research and development	130,500	$ 130,486	$ 0	$ 130,486	$ 0
Cash acquired	(3,000)			$ (3,035)
Total cost to acquire asset	113,300
Series A Preferred Stock and common stock
Asset Acquisition [Line Items]
Consideration transferred	$ 110,000