Amount to be paid under agreement.

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Minority interest ownership percentage by noncontrolling owners held in third party.

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Percentage of annual equity grant of options to purchase outstanding shares of common stock.

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Reimbursable research costs.

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Related party expenses incurred prior to asset acquisition.

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Related party expenses unpaid prior to asset acquisition.

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Research initiation fees.

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The equity interest of noncontrolling shareholders, partners or other equity holders in consolidated entity.

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The cash outflow from advancing money to an affiliate (an entity that is related but not strictly controlled by the entity).

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Amount of noncash expense for share-based payment arrangement.

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Related Party Transactions - Additional Information (Details) - USD ($)		3 Months Ended		6 Months Ended
	Jun. 22, 2023	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022	Dec. 31, 2023	Jul. 12, 2023
Related Party Transaction [Line Items]
Stock compensation expense				$ 3,620,000	$ 4,118,000
Parapyre Option Obligation
Related Party Transaction [Line Items]
Stock compensation expense		$ 200,000		200,000
Parapyre Option Obligation \| Forecast
Related Party Transaction [Line Items]
Percentage of annual equity grant of options						1.00%
Paragon Agreement
Related Party Transaction [Line Items]
Related party expenses incurred prior to asset acquisition	$ 19,300,000
Related party expenses unpaid prior to asset acquisition	19,300,000
Research initiation fees	3,000,000.0
Reimbursable research costs	$ 16,300,000
Cash payments made to Paragon		$ 0	$ 0	$ 0	$ 0
Paragon
Related Party Transaction [Line Items]
Percentage of ownership		5.00%		5.00%
Paragon \| SPY001 License Agreement \| Maximum \| Subsequent Event
Related Party Transaction [Line Items]
Contingent obligation based on milestones							$ 22,000,000.0
Fairmount Funds Management LLC
Related Party Transaction [Line Items]
Percentage of ownership		5.00%		5.00%
Percentage of ownership held in third party		5.00%		5.00%