Stockholders' Equity - Summary of Pre-funded Warrants for Common Stock Issued and Outstanding (Details) - $ / shares	12 Months Ended
Dec. 31, 2022	May 31, 2022
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Exercise Price	$ 0.0001	$ 0.0001
Pre-funded Warrants
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of Warrants Outstanding	28,891,578
Pre-funded Warrants \| February 2019
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Issue Date	Feb. 28, 2019
Expiration Date	None
Exercise Price	$ 0.0001
Number of Warrants Outstanding	3,750,000
Pre-funded Warrants \| April 2020
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Issue Date	Apr. 30, 2020
Expiration Date	None
Exercise Price	$ 0.0001
Number of Warrants Outstanding	11,860,328
Pre-funded Warrants \| May 2022
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Issue Date	May 31, 2022
Expiration Date	None
Exercise Price	$ 0.0001
Number of Warrants Outstanding	13,281,250

Warrant expiration date.

No definition available.

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Namespace Prefix:	agle_
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- Definition

Date the warrants or rights are exercisable, in YYYY-MM-DD format.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 505
-SubTopic 10
-Section 50
-Paragraph 3
-URI https://asc.fasb.org/extlink&oid=126973232&loc=d3e21475-112644

+ Details

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- Definition

Exercise price per share or per unit of warrants or rights outstanding.

+ References

+ Details

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- Definition

Number of warrants or rights outstanding.

+ References

No definition available.

+ Details

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

+ Details

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