Consolidated Statements of Operations - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Revenue:
Total revenue	$ 2,329	$ 18,739	$ 0
Operating expenses:
Research and development	58,579	57,069	59,638
General and administrative	28,531	27,319	21,843
Total operating expenses	87,110	84,388	81,481
Loss from operations	(84,781)	(65,649)	(81,481)
Other income (expense):
Interest income	837	111	593
Other expense, net	(7)	(122)	(5)
Total other income (expense)	830	(11)	588
Loss before income tax expense	(83,951)	(65,660)	(80,893)
Income tax expense	136	(141)	0
Net loss	$ (83,815)	$ (65,801)	$ (80,893)
Net loss per share, basic	$ (0.99)	$ (1.00)	$ (1.52)
Net loss per share, diluted	$ (0.99)	$ (1.00)	$ (1.52)
Weighted-average common shares outstanding, basic	84,280,785	65,744,611	53,371,730
Weighted-average common shares outstanding, diluted	84,280,785	65,744,611	53,371,730
License [Member]
Revenue:
Total revenue	$ 0	$ 12,000	$ 0
Development Fee [Member]
Revenue:
Total revenue	$ 2,329	$ 6,739	$ 0