X0206 3 2021-08-16 0 0001633932 ESSA Pharma Inc. EPIX 0001259869 BIOTECH GROWTH N V ARA HILL TOP BUILDING, UNIT A-5, PLETTERIJWEG OOST 1 CURACAO P8 00000 NETHERLANDS ANTILLES 0 0 1 0 0000924223 BB BIOTECH AG SCHWERTSTRASSE 6 SCHAFFHAUSEN V8 CH-8200 SWITZERLAND 0 0 1 0 Common Shares 4765814 D Biotech Growth N.V. is a wholly-owned subsidiary of BB Biotech AG. Accordingly, BB Biotech AG may be deemed to be the indirect beneficial owner of the securities of ESSA Pharma Inc. held directly or indirectly by Biotech Growth N.V. The Form 3 is jointly filed by BB Biotech AG and Biotech Growth N.V. /s/ Martin Gubler 2021-08-16 /s/ Daniel Koller 2021-08-16