The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA PHARMACEUTICALS INC Common 004225108 10,696 329,500 SH   SOLE   329,500 0 0
AGENUS INC Common 00847G705 12,554 3,099,838 SH   SOLE   3,099,838 0 0
AKEBIA THERAPEUTICS INC Common 00972D105 4,652 621,873 SH   SOLE   621,873 0 0
AMICUS THERAPEUTICS INC Common 03152W109 20,195 3,698,665 SH   SOLE   3,698,665 0 0
ASSEMBLY BIOSCIENCES INC Common 045396108 1,448 260,982 SH   SOLE   260,982 0 0
BIOMARIN PHARMACEUTICAL INC Common 09061G101 33,685 432,972 SH   SOLE   432,972 0 0
BRISTOL MYERS SQUIBB CO. Common 110122108 32,755 445,339 SH   SOLE   445,339 0 0
CASCADIAN THERAPEUTICS INC Common 14740B101 5,418 5,744,723 SH   SOLE   5,744,723 0 0
CELATOR PHARMACEUTICALS INC. Common 15089R102 33,942 1,124,666 SH   SOLE   1,124,666 0 0
CELLECTIS - ADR Sponsored ADS 15117K103 1,135 42,671 SH   SOLE   42,671 0 0
CORVUS PHARMACEUTICALS INC Common 221015100 1,067 74,800 SH   SOLE   74,800 0 0
CYTOKINETICS INC. Common 23282W605 4,782 503,900 SH   SOLE   503,900 0 0
DERMIRA INC Common 24983L104 21,109 721,663 SH   SOLE   721,663 0 0
FORTRESS BIOTECH INC Common 34960Q109 3,569 1,326,636 SH   SOLE   1,326,636 0 0
GILEAD SCIENCES INC Common 375558103 9,051 108,500 SH   SOLE   108,500 0 0
GLOBAL BLOOD THERAPEEUTICS INC Common 37890U108 15,987 963,646 SH   SOLE   963,646 0 0
IMMUNOMEDICS INC Common 452907108 19,852 8,556,957 SH   SOLE   8,556,957 0 0
IMMUNOMEDICS INC Common 452907108 45 300,800 SH Call SOLE   300,800 0 0
IMMUNOMEDICS INC Common 452907108 19 153,100 SH Call SOLE   153,100 0 0
INNOCOLL HOLDINGS PLC Sh G4783X105 2,579 468,148 SH   SOLE   468,148 0 0
ISh RUSSELL 2000 ETF Put 464287955 19 50,000 SH Put SOLE   50,000 0 0
LA JOLLA PHARMACEUTICAL CO Common 503459604 1,120 70,000 SH   SOLE   70,000 0 0
LION BIOTECHNOLOGIES INC Common 53619R102 35,142 4,338,557 SH   SOLE   4,338,557 0 0
MEDIVATION INC Common 58501N101 16,866 279,700 SH   SOLE   279,700 0 0
MIRATI THERAPEUTICS INC Common 60468T105 6,633 1,214,833 SH   SOLE   1,214,833 0 0
NANTKWEST INC Common 63016Q102 450 72,412 SH   SOLE   72,412 0 0
NEUROCRINE BIOSCIENCES INC Common 64125C109 23,149 509,330 SH   SOLE   509,330 0 0
NEURODERM LTD Common M74231107 9,051 557,003 SH   SOLE   557,003 0 0
ONCOBIOLOGICS INC Common 68235M105 1,587 466,667 SH   SOLE   466,667 0 0
ONCOBIOLOGICS INC - WARRANT A Warrant 68235M113 107 233,333 SH   SOLE   233,333 0 0
ONCOBIOLOGICS INC - WARRANT B Warrant 68235M121 105 233,333 SH   SOLE   233,333 0 0
PERNIX THERAPEUTICS HOLDINGS INC Convertible Debt 71426VAK4 1,487 7,000,000 PRN   SOLE   7,000,000 0 0
RELYPSA INC Common 759531106 11,346 613,300 SH   SOLE   613,300 0 0
SAREPTA THERAPUTICS INC Common 803607100 26,930 1,412,190 SH   SOLE   1,412,190 0 0
SAREPTA THERAPUTICS INC Common 803607100 44 5,600 SH Call SOLE   5,600 0 0
SAREPTA THERAPUTICS INC Common 803607100 2,090 380,000 SH Call SOLE   380,000 0 0
SAREPTA THERAPUTICS INC Common 803607100 208 100,000 SH Call SOLE   100,000 0 0
SAREPTA THERAPUTICS INC Common 803607100 261 139,000 SH Call SOLE   139,000 0 0
SAREPTA THERAPUTICS INC Common 803607100 1 2,900 SH Put SOLE   2,900 0 0
SAREPTA THERAPUTICS INC Common 803607100 1,913 1,275,600 SH Put SOLE   1,275,600 0 0
SAREPTA THERAPUTICS INC Common 803607100 92 53,500 SH Put SOLE   53,500 0 0
SORRENTO THERAPEUTICS INC Common 83587F202 9,270 1,655,274 SH   SOLE   1,655,274 0 0
TELIGENT INC. Common 87960W104 9,211 1,290,000 SH   SOLE   1,290,000 0 0
TESARO INC Common 881569107 43,202 514,000 SH   SOLE   514,000 0 0
TRILLIUM THERAPEUTICS INC Common 89620X506 2,054 228,697 SH   SOLE   228,697 0 0
VANDA PHARMACEUTICALS INC Common 921659108 7,940 709,579 SH   SOLE   709,579 0 0
VERACYTE INC Common 92337F107 4,620 918,556 SH   SOLE   918,556 0 0
VERICEL CORP Common 92346J108 574 255,000 SH   SOLE   255,000 0 0