The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ALKERMES PLC Common G01767105   42,432,000 1,200,000 SH   SOLE   1,200,000 0 0
APELLIS PHARMACEUTICALS INC Common 03753U106   491,699,991 12,222,222 SH   SOLE   12,222,222 0 0
ARGENX SE Sponsored ADR 04016X101   730,250,000 1,000,000 SH   SOLE   1,000,000 0 0
ARROWHEAD PHARMACEUTICALS INC Common 04280A100   670,889,937 10,699,999 SH   SOLE   10,699,999 0 0
ASCENDIS PHARMA Sponsored ADR 04351P101   1,157,945,625 5,062,500 SH   SOLE   5,062,500 0 0
AVALO THERAPEUTICS Common 05338F306   21,051,300 1,410,000 SH   SOLE   1,410,000 0 0
CELCUITY INC Common 15102K100   3,050,000 200,000 SH Call SOLE   200,000 0 0
CELCUITY INC Common 15102K100   385,222,500 3,375,000 SH   SOLE   3,375,000 0 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100   454,017,673 11,430,455 SH   SOLE   11,430,455 0 0
CYTOKINETICS INC Common 23282W605   219,699,978 3,333,333 SH   SOLE   3,333,333 0 0
DAMORA THERAPEUTICS INC Common 36322Q206   97,979,700 3,783,000 SH   SOLE   3,783,000 0 0
DEFINIUM THERAPEUTICS INC Common 24477V105   94,500,000 5,000,000 SH   SOLE   5,000,000 0 0
GH RESEARCH PLC ORDINARY SHARES G3855L106   25,308,000 1,800,000 SH   SOLE   1,800,000 0 0
KRYSTAL BIOTECH INC Common 501147102   746,257,548 2,888,888 SH   SOLE   2,888,888 0 0
KYMERA THERAPEUTICS INC Common 501575104   622,571,678 7,474,747 SH   SOLE   7,474,747 0 0
LEXEO THERAPEUTICS INC Common 52886X107   10,762,500 1,875,000 SH   SOLE   1,875,000 0 0
MADRIGAL PHARMACEUTICALS INC Common 558868105   951,763,208 1,818,181 SH   SOLE   1,818,181 0 0
MANNKIND CORP Common 56400P706   5,390,000 2,200,000 SH   SOLE   2,200,000 0 0
OCULAR THERAPEUTIX INC Common 67576A100   104,308,050 12,315,000 SH   SOLE   12,315,000 0 0
REVOLUTION MEDICINES INC Common 76155X100   227,997,179 2,344,444 SH   SOLE   2,344,444 0 0
SEPTERNA INC Common 81734D104   32,140,125 1,337,500 SH   SOLE   1,337,500 0 0
SOLENO THERAPEUTICS INC Common 834203309   77,004,000 2,300,000 SH   SOLE   2,300,000 0 0
STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106   315,977,751 6,555,555 SH   SOLE   6,555,555 0 0
TAYSHA GENE THERAPIES INC Common 877619106   96,999,000 21,700,000 SH   SOLE   21,700,000 0 0
TERNS PHARMACEUTICALS INC Common 880881107   300,240,400 5,695,000 SH   SOLE   5,695,000 0 0
UNIQURE NV Common N90064101   97,439,378 5,959,595 SH   SOLE   5,959,595 0 0
UNITED THERAPEUTICS CORP Common 91307C102   1,559,537,400 2,630,000 SH   SOLE   2,630,000 0 0
UNITED THERAPEUTICS CORP Common 91307C102   5,688,000 200,000 SH Call SOLE   200,000 0 0
UNITED THERAPEUTICS CORP Common 91307C102   4,608,000 180,000 SH Call SOLE   180,000 0 0
VERA THERAPEUTICS INC Common 92337R101   236,909,964 5,888,888 SH   SOLE   5,888,888 0 0
VIRIDIAN THERAPEUTICS INC Common 92790C104   29,340,000 1,500,000 SH   SOLE   1,500,000 0 0
WHITEHAWK THERAPEUTICS INC Common 00032Q104   9,830,437 2,849,402 SH   SOLE   2,849,402 0 0
XENON PHARMACEUTICALS INC Common 98420N105   335,977,733 5,777,777 SH   SOLE   5,777,777 0 0