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The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
89BIO INC Common 282559103   93,900,513 6,387,790 SH   SOLE   6,387,790 0 0
AKERO THERAPEUTICS INC Common 00973Y108   187,809,751 3,955,555 SH   SOLE   3,955,555 0 0
ALKERMES PLC Common G01767105   67,200,000 2,240,000 SH   SOLE   2,240,000 0 0
AMICUS THERAPEUTICS INC. Common 03152W109   118,397,000 15,025,000 SH   SOLE   15,025,000 0 0
APELLIS PHARMACEUTICALS INC. Common 03753U106   276,588,884 12,222,222 SH   SOLE   12,222,222 0 0
ARGENX SE Sponsored ADR 04016X101   730,184,400 990,000 SH   SOLE   990,000 0 0
ARROWHEAD PHARMACEUTICALS INC. Common 04280A100   375,941,000 10,900,000 SH   SOLE   10,900,000 0 0
ASCENDIS PHARMA Sponsored ADR 04351P101   1,015,919,100 5,110,000 SH   SOLE   5,110,000 0 0
AVIDITY BIOSCIENCES INC Common 05370A108   333,092,650 7,645,000 SH   SOLE   7,645,000 0 0
BIOCRYST PHARMACEUTICALS INC Common 09058V103   9,487,500 1,250,000 SH   SOLE   1,250,000 0 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADR 152309100   262,095,940 10,808,080 SH   SOLE   10,808,080 0 0
KRYSTAL BIOTECH INC Common 501147102   490,360,974 2,777,777 SH   SOLE   2,777,777 0 0
KYMERA THERAPEUTICS INC Common 501575104   359,410,000 6,350,000 SH   SOLE   6,350,000 0 0
MADRIGAL PHARMACEUTICALS INC Common 558868105   840,723,780 1,833,000 SH   SOLE   1,833,000 0 0
MANNKIND CORP Common 56400P706   23,997,869 4,468,877 SH   SOLE   4,468,877 0 0
MERUS N V Common N5749R100   333,526,375 3,542,500 SH   SOLE   3,542,500 0 0
MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104   14,340,000 2,000,000 SH   SOLE   2,000,000 0 0
OCULAR THERAPEUTIX INC Common 67576A100   119,822,500 10,250,000 SH   SOLE   10,250,000 0 0
ORUKA THERAPEUTICS INC Common 687604108   25,640,128 1,333,340 SH   SOLE   1,333,340 0 0
SEPTERNA INC Common 81734D104   25,158,375 1,337,500 SH   SOLE   1,337,500 0 0
SOLENO THERAPEUTICS INC Common 834203309   174,257,725 2,577,777 SH   SOLE   2,577,777 0 0
STRUCTURE THERAPEUTICS INC. SPONSORED ADS 86366E106   144,355,540 5,155,555 SH   SOLE   5,155,555 0 0
STRUCTURE THERAPEUTICS INC. SPONSORED ADS 86366E106   2,237,500 250,000 SH Call SOLE   250,000 0 0
TANGO THERAPEUTICS INC Common 87583X109   4,578,000 545,000 SH   SOLE   545,000 0 0
TAYSHA GENE THERAPIES INC Common 877619106   70,959,000 21,700,000 SH   SOLE   21,700,000 0 0
TOURMALINE BIO INC Common 89157D105   122,232,196 2,555,555 SH   SOLE   2,555,555 0 0
UNIQURE NV Common N90064101   259,422,196 4,444,444 SH   SOLE   4,444,444 0 0
UNITED THERAPEUTICS CORP Common 91307C102   847,735,685 2,022,222 SH   SOLE   2,022,222 0 0
UNITED THERAPEUTICS CORP Common 91307C102   4,440,000 200,000 SH Call SOLE   200,000 0 0
VERA THERAPEUTICS INC Common 92337R101   180,462,600 6,210,000 SH   SOLE   6,210,000 0 0
WHITEHAWK THERAPEUTICS INC Common 00032Q104   5,413,864 2,849,402 SH   SOLE   2,849,402 0 0
XENON PHARMACEUTICALS INC Common 98420N105   216,810,000 5,400,000 SH   SOLE   5,400,000 0 0