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The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AADI BIOSCIENCES INC Common 00032Q104   5,869,768 2,849,402 SH   SOLE   2,849,402 0 0
AMICUS THERAPEUTICS INC. Common 03152W109   247,509,000 23,175,000 SH   SOLE   23,175,000 0 0
APELLIS PHARMACEUTICALS INC. Common 03753U106   320,444,441 11,111,111 SH   SOLE   11,111,111 0 0
ARGENX SE Sponsored ADR 04016X101   671,348,191 1,238,467 SH   SOLE   1,238,467 0 0
ARROWHEAD PHARMACEUTICALS INC. Common 04280A100   172,177,761 8,888,888 SH   SOLE   8,888,888 0 0
ASCENDIS PHARMA Sponsored ADR 04351P101   744,890,867 4,988,888 SH   SOLE   4,988,888 0 0
AUTOLUS THERAPEUTICS PLC Sponsored ADR 05280R100   44,814,811 12,345,678 SH   SOLE   12,345,678 0 0
AVIDITY BIOSCIENCES INC Common 05370A108   315,768,750 6,875,000 SH   SOLE   6,875,000 0 0
BIOCRYST PHARMACEUTICALS INC Common 09058V103   90,174,000 11,865,000 SH   SOLE   11,865,000 0 0
BIOMARIN PHARMACEUTICAL INC Common 09061G101   143,252,074 2,038,015 SH   SOLE   2,038,015 0 0
CG ONCOLOGY INC Common 156944100   26,411,000 700,000 SH   SOLE   700,000 0 0
DYNE THERAPEUTICS INC. Common 26818M108   23,348,000 650,000 SH   SOLE   650,000 0 0
INTRA-CELLULAR THERAPIES INC Common 46116X101   223,168,500 3,050,000 SH   SOLE   3,050,000 0 0
IOVANCE BIOTHERAPEUTICS INC Common 462260100   39,813,600 4,240,000 SH   SOLE   4,240,000 0 0
KRYSTAL BIOTECH INC Common 501147102   477,323,071 2,622,222 SH   SOLE   2,622,222 0 0
KURA ONCOLOGY INC Common 50127T109   69,201,008 3,541,505 SH   SOLE   3,541,505 0 0
KYMERA THERAPEUTICS INC Common 501575104   212,985,000 4,500,000 SH   SOLE   4,500,000 0 0
MADRIGAL PHARMACEUTICALS INC Common 558868105   430,594,380 2,029,000 SH   SOLE   2,029,000 0 0
MANNKIND CORP Common 56400P706   55,037,500 8,750,000 SH   SOLE   8,750,000 0 0
MERUS N V Common N5749R100   67,695,800 1,355,000 SH   SOLE   1,355,000 0 0
MONTE ROSA THERAPEUTICS INC Common 61225M102   30,688,251 5,790,236 SH   SOLE   5,790,236 0 0
MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104   139,668,442 2,770,100 SH   SOLE   2,770,100 0 0
NEUROGENE INC Common 64135M105   924,337 22,029 SH   SOLE   22,029 0 0
OCULAR THERAPEUTIX INC Common 67576A100   70,122,000 8,060,000 SH   SOLE   8,060,000 0 0
SAREPTA THERAPEUTICS INC Common 803607100   319,163,264 2,555,555 SH   SOLE   2,555,555 0 0
SOLENO THERAPEUTICS INC Common 834203309   110,118,690 2,181,000 SH   SOLE   2,181,000 0 0
SPYRE THERAPEUTICS INC Common 00773J202   17,604,826 598,600 SH   SOLE   598,600 0 0
SYNDAX PHARMACEUTICALS INC Common 87164F105   74,852,412 3,888,437 SH   SOLE   3,888,437 0 0
TAYSHA GENE THERAPIES INC Common 877619106   37,486,500 18,650,000 SH   SOLE   18,650,000 0 0
TOURMALINE BIO INC Common 89157D105   57,133,328 2,222,222 SH   SOLE   2,222,222 0 0
ULTRAGENYX PHARMACEUTICAL INC Common 90400D108   46,106,500 830,000 SH   SOLE   830,000 0 0
UNITED THERAPEUTICS CORP Common 91307C102   1,024,482,515 2,858,888 SH   SOLE   2,858,888 0 0
VAXCYTE INC Common 92243G108   134,267,250 1,175,000 SH   SOLE   1,175,000 0 0
VERA THERAPEUTICS INC Common 92337R101   190,483,878 4,309,590 SH   SOLE   4,309,590 0 0
XENON PHARMACEUTICALS INC Common 98420N105   223,096,640 5,666,666 SH   SOLE   5,666,666 0 0
INSMED INC Common 457669957   125,000 50,000 SH Put SOLE   50,000 0 0