0001104659-22-060934.txt : 20220516 0001104659-22-060934.hdr.sgml : 20220516 20220516085723 ACCESSION NUMBER: 0001104659-22-060934 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20220331 FILED AS OF DATE: 20220516 DATE AS OF CHANGE: 20220516 EFFECTIVENESS DATE: 20220516 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Avoro Capital Advisors LLC CENTRAL INDEX KEY: 0001633313 IRS NUMBER: 271007403 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-16573 FILM NUMBER: 22925816 BUSINESS ADDRESS: STREET 1: 110 GREENE STREET STREET 2: SUITE 800 CITY: NEW YORK STATE: NY ZIP: 10012 BUSINESS PHONE: 212-937-4975 MAIL ADDRESS: STREET 1: 110 GREENE STREET STREET 2: SUITE 800 CITY: NEW YORK STATE: NY ZIP: 10012 FORMER COMPANY: FORMER CONFORMED NAME: venBio Select Advisor LLC DATE OF NAME CHANGE: 20150210 13F-HR 1 primary_doc.xml 13F-HR LIVE false false false 0001633313 XXXXXXXX 03-31-2022 03-31-2022 false Avoro Capital Advisors LLC

110 Greene Street Suite 800 New York NY 10012

13F HOLDINGS REPORT 028-16573 N Scott Epstein 212-937-4975 /s/ Scott Epstein New York NY 04-18-2022 0 43 5477562 INFORMATION TABLE 2 infotable.xml AADI BIOSCIENCES INC Common 00032Q104 31045 1829402 SH SOLE 1829402 0 0 ACADIA PHARMACEUTICALS INC Common 004225108 55101 2275000 SH SOLE 2275000 0 0 ADVERUM BIOTECHNOLOGIES INC Common 00773U108 9105 6950000 SH SOLE 6950000 0 0 ALNYLAM PHARMACEUTICALS INC Common 02043Q107 212277 1300000 SH SOLE 1300000 0 0 AMARIN CORP PLC Sponsored ADR 023111206 19740 6000000 SH SOLE 6000000 0 0 AMICUS THERAPEUTICS INC Common 03152W109 194135 20500000 SH SOLE 20500000 0 0 APELLIS PHARMACEUTICALS INC Common 03753U106 480155 9450000 SH SOLE 9450000 0 0 APPLIED MOLECULAR TRANS INC Common 03824M109 7746 1030000 SH SOLE 1030000 0 0 ARGENX SE Sponsored ADR 04016X101 395714 1255000 SH SOLE 1255000 0 0 ASCENDIS PHARMA Sponsored ADR 04351P101 258192 2200000 SH SOLE 2200000 0 0 AVADEL PHARMACEUTICALS PLC Sponsored ADR 05337M104 11406 1670000 SH SOLE 1670000 0 0 AVIDITY BIOSCIENCES INC Common 05370A108 24011 1300000 SH SOLE 1300000 0 0 BIOCRYST PHARMACEUTICLAS INC Common 09058V103 30488 1875000 SH SOLE 1875000 0 0 BIOMARIN PHARMACEUTICAL INC Common 09061G101 233999 3035000 SH SOLE 3035000 0 0 CYMABAY THERAPEUTICS INC Common 23257D103 32033 10300000 SH SOLE 10300000 0 0 DESIGN THERAPEUTICS INC Common 25056L103 35889 2222222 SH SOLE 2222222 0 0 DICE THERAPEUTICS INC Common 23345J104 20565 1075000 SH SOLE 1075000 0 0 FENNEC PHARMACEUTICALS INC Common 31447P100 6720 1200000 SH SOLE 1200000 0 0 GENOCEA BIOSCIENCES INC Common 372427401 6355 5084184 SH SOLE 5084184 0 0 HORIZON THERAPEUTICS PLC Common G46188101 683865 6500000 SH SOLE 6500000 0 0 IO BIOTECH INC Common 449778109 9580 2055883 SH SOLE 2055883 0 0 IOVANCE BIOTHERAPEUTICS INC Common 462260100 151931 9125000 SH SOLE 9125000 0 0 IVERIC BIO INC Common 46583P102 122018 7250000 SH SOLE 7250000 0 0 KRYSTAL BIOTECH INC Common 501147102 66873 1005000 SH SOLE 1005000 0 0 KURA ONCOLOGY INC Common 50127T109 77184 4800000 SH SOLE 4800000 0 0 KYMERA THERAPEUTICS INC Common 501575104 34554 816500 SH SOLE 816500 0 0 MADRIGAL PHARMACEUTICALS INC Common 558868105 139821 1425000 SH SOLE 1425000 0 0 MANNKIND CORP Common 56400P706 32384 8800000 SH SOLE 8800000 0 0 MARINUS PHARMACEUTICALS INC Common 56854Q200 29453 3150000 SH SOLE 3150000 0 0 MERSANA THERAPEUTICS INC Common 59045L106 27132 6800000 SH SOLE 6800000 0 0 MIRATI THERAPEUTICS INC Common 60468T105 437822 5325000 SH SOLE 5325000 0 0 MONTE ROSA THERAPEUTICS INC Common 61225M102 46426 3311434 SH SOLE 3311434 0 0 NUVALENT INC Common 670703107 14577 1049471 SH SOLE 1049471 0 0 PMV PHARMACEUTICALS INC Common 69353Y103 45804 2200000 SH SOLE 2200000 0 0 PRAXIS PRECISION MEDICINES INC Common 74006W108 21952 2150000 SH SOLE 2150000 0 0 SAREPTA THERAPEUTICS INC Common 803607100 244906 3135000 SH SOLE 3135000 0 0 SEAGEN INC Common 81181C104 189426 1315000 SH SOLE 1315000 0 0 SPDR SERIES TRUST - S&P BIOTECH ETF 78464A870 274134 3050000 SH SOLE 3050000 0 0 SYNDAX PHARMACEUTICALS INC Common 87164F105 38592 2220500 SH SOLE 2220500 0 0 TANGO THERAPEUTICS INC Common 87583X109 11749 1550000 SH SOLE 1550000 0 0 ULTRAGENYX PHARMACEUTICAL INC Common 90400D108 16703 230000 SH SOLE 230000 0 0 UNITED THERAPEUTICS CORP Common 91307C102 543612 3030000 SH SOLE 3030000 0 0 XENON PHARMACEUTICALS INC Common 98420N105 152391 4985000 SH SOLE 4985000 0 0