0001104659-24-061613.txt : 20240515 0001104659-24-061613.hdr.sgml : 20240515 20240515080734 ACCESSION NUMBER: 0001104659-24-061613 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20240331 FILED AS OF DATE: 20240515 DATE AS OF CHANGE: 20240515 EFFECTIVENESS DATE: 20240515 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Avoro Capital Advisors LLC CENTRAL INDEX KEY: 0001633313 ORGANIZATION NAME: IRS NUMBER: 271007403 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-16573 FILM NUMBER: 24947265 BUSINESS ADDRESS: STREET 1: 110 GREENE STREET STREET 2: SUITE 800 CITY: NEW YORK STATE: NY ZIP: 10012 BUSINESS PHONE: 212-937-4975 MAIL ADDRESS: STREET 1: 110 GREENE STREET STREET 2: SUITE 800 CITY: NEW YORK STATE: NY ZIP: 10012 FORMER COMPANY: FORMER CONFORMED NAME: venBio Select Advisor LLC DATE OF NAME CHANGE: 20150210 13F-HR 1 primary_doc.xml X0202 13F-HR LIVE false false false 0001633313 XXXXXXXX 03-31-2024 03-31-2024 false Avoro Capital Advisors LLC

110 Greene Street Suite 800 New York NY 10012

13F HOLDINGS REPORT 028-16573 000154091 801-74391 N Scott Epstein 212-937-4975 /s/ Scott Epstein New York NY 04-29-2024 0 46 8573512829 INFORMATION TABLE 2 infotable.xml AADI BIOSCIENCES INC Common 00032Q104 6667601 2849402 SH SOLE 2849402 0 0 ALNYLAM PHARMACEUTICALS INC Common 02043Q107 44835000 300000 SH SOLE 300000 0 0 ALPINE IMMUNE SCIENCES INC Common 02083G100 228921000 5775000 SH SOLE 5775000 0 0 AMICUS THERAPEUTICS INC Common 03152W109 322772000 27400000 SH SOLE 27400000 0 0 APELLIS PHARMACEUTICALS INC Common 03753U106 653111105 11111111 SH SOLE 11111111 0 0 ARGENX SE Sponsored ADR 04016X101 487609227 1238467 SH SOLE 1238467 0 0 ARROWHEAD PHARMACEUTICALS INC Common 04280A100 244688873 8555555 SH SOLE 8555555 0 0 ASCENDIS PHARMA Sponsored ADR 04351P101 599640899 3966666 SH SOLE 3966666 0 0 AUTOLUS THERAPEUTICS PLC Sponsored ADR 05280R100 78765426 12345678 SH SOLE 12345678 0 0 AVIDITY BIOSCIENCES INC Common 05370A108 148654000 5825000 SH SOLE 5825000 0 0 ADVERUM BIOTECHNOLOGIES INC Common 00773U207 5891657 416666 SH SOLE 416666 0 0 BIOCRYST PHARMACEUTICALS INC Common 09058V103 66294000 13050000 SH SOLE 13050000 0 0 BIOMARIN PHARMACEUTICAL INC Common 09061G101 381239100 4365000 SH SOLE 4365000 0 0 CEREVEL THERAPEUTICS HLDNG Common 15678U128 319373310 7555555 SH SOLE 7555555 0 0 CG ONCOLOGY INC Common 156944100 30730000 700000 SH SOLE 700000 0 0 CRISPR THERAPEUTICS AG Common H17182108 28598573 419580 SH SOLE 419580 0 0 INTRA-CELLULAR THERAPIES INC Common 46116X101 171270000 2475000 SH SOLE 2475000 0 0 IOVANCE BIOTHERAPEUTICS INC Common 462260100 173394000 11700000 SH SOLE 11700000 0 0 KRYSTAL BIOTECH INC Common 501147102 454709901 2555555 SH SOLE 2555555 0 0 KURA ONCOLOGY INC Common 50127T109 82120500 3850000 SH SOLE 3850000 0 0 KYMERA THERAPEUTICS INC Common 501575104 156333298 3888888 SH SOLE 3888888 0 0 KYVERNA THERAPEUTICS INC Common 501976104 11799000 475000 SH SOLE 475000 0 0 MACROGENICS INC Common 556099109 90528000 6150000 SH SOLE 6150000 0 0 MADRIGAL PHARMACEUTICALS INC Common 558868105 519244326 1944444 SH SOLE 1944444 0 0 MANNKIND CORP Common 56400P706 40770000 9000000 SH SOLE 9000000 0 0 MARINUS PHARMACEUTICALS INC Common 56854Q200 37431087 4140607 SH SOLE 4140607 0 0 MERUS N V Common N5749R100 40026627 888888 SH SOLE 888888 0 0 MONTE ROSA THERAPEUTICS INC Common 61225M102 31971750 4535000 SH SOLE 4535000 0 0 MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104 129593400 2580000 SH SOLE 2580000 0 0 OCULAR THERAPEUTIX INC Common 67576A100 65055318 7148936 SH SOLE 7148936 0 0 ROCKET PHARMACEUTICALS INC Common 77313F106 33968646 1260900 SH SOLE 1260900 0 0 ROIVANT SCIENCES LTD Common G76279101 49023247 4651162 SH SOLE 4651162 0 0 SAREPTA THERAPEUTICS INC Common 803607100 562431720 4344444 SH SOLE 4344444 0 0 SOLENO THERAPEUTICS INC Common 834203309 69550000 1625000 SH SOLE 1625000 0 0 SPDR SERIES TRUST - S&P BIOTECH ETF 78464A870 408027000 4300000 SH SOLE 4300000 0 0 SPYRE THERAPEUTICS INC Common 00773J202 69758504 1839138 SH SOLE 1839138 0 0 SYNDAX PHARMACEUTICALS INC Common 87164F105 100488884 4222222 SH SOLE 4222222 0 0 TAYSHA GENE THERAPIES INC Common 877619106 53525500 18650000 SH SOLE 18650000 0 0 TOURMALINE BIO INC Common 89157D105 50888884 2222222 SH SOLE 2222222 0 0 ULTRAGENYX PHARMACEUTICAL INC Common 90400D108 38752700 830000 SH SOLE 830000 0 0 UNITED THERAPEUTICS CORP Common 91307C102 656743751 2858888 SH SOLE 2858888 0 0 VAXCYTE INC Common 92243G108 39278250 575000 SH SOLE 575000 0 0 VERA THERAPEUTICS INC Common 92337R101 227026800 5265000 SH SOLE 5265000 0 0 VERRICA PHARMACEUTICALS INC Common 92511W108 23679994 3999999 SH SOLE 3999999 0 0 VIKING THERAPEUTICS INC Common 92686J106 294380000 3590000 SH SOLE 3590000 0 0 XENON PHARMACEUTICALS INC Common 98420N105 243949971 5666666 SH SOLE 5666666 0 0