The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
NOVO-NORDISK A S ADR 670100205 15,871 336,670 SH   SOLE   336,670 0 0
ABBOTT LABS COM 002824100 47 639 SH   SOLE   639 0 0
ALLEGHANY CORP DEL COM 017175100 199 305 SH   SOLE   305 0 0
ALPHABET INC CAP STK CL A 02079K305 5,507 4,562 SH   SOLE   4,562 0 0
ALPHABET INC CAP STK CL C 02079K107 16,951 14,203 SH   SOLE   14,203 0 0
BANK OF NT BUTTERFIELD&SON L SHS NEW G0772R208 39 750 SH   SOLE   750 0 0
BERKSHIRE HATHAWAY INC DEL CL A 084670108 640 2 SH   SOLE   2 0 0
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 657 3,070 SH   SOLE   3,070 0 0
BROWN FORMAN CORP CL B 115637209 192 3,800 SH   SOLE   3,800 0 0
CIMAREX ENERGY CO COM 171798101 15,516 166,950 SH   SOLE   166,950 0 0
CLOROX CO DEL COM 189054109 18,666 124,100 SH   SOLE   124,100 0 0
COCA COLA CO COM 191216100 97 2,100 SH   SOLE   2,100 0 0
CONOCOPHILLIPS COM 20825C104 62 800 SH   SOLE   800 0 0
DIGIMARC CORP NEW COM 25381B101 8,085 257,089 SH   SOLE   257,089 0 0
ENSTAR GROUP LIMITED SHS G3075P101 7,068 33,900 SH   SOLE   33,900 0 0
EXXON MOBIL CORP COM 30231G102 61 715 SH   SOLE   715 0 0
INTREXON CORP COM 46122T102 3,540 205,557 SH   SOLE   205,557 0 0
JOHNSON & JOHNSON COM 478160104 1,016 7,350 SH   SOLE   7,350 0 0
MASTERCARD INCORPORATED CL A 57636Q104 268 1,206 SH   SOLE   1,206 0 0
MICROSOFT CORP COM 594918104 523 4,570 SH   SOLE   4,570 0 0
PHILLIPS 66 COM 718546104 22 197 SH   SOLE   197 0 0
PTC INC COM 69370C100 9,983 94,011 SH   SOLE   94,011 0 0
REGENERON PHARMACEUTICALS COM 75886F107 23,204 57,431 SH   SOLE   57,431 0 0
RENAISSANCERE HOLDINGS LTD COM G7496G103 4,785 35,824 SH   SOLE   35,824 0 0
SEATTLE GENETICS INC COM 812578102 7,197 93,316 SH   SOLE   93,316 0 0
SENOMYX INC COM 81724Q107 2,094 1,414,863 SH   SOLE   1,414,863 0 0
SPDR GOLD TRUST GOLD SHS 78463V107 73 650 SH   SOLE   650 0 0
STITCH FIX INC COM CL A 860897107 19,930 455,344 SH   SOLE   455,344 0 0
TESLA INC COM 88160R101 10,632 40,155 SH   SOLE   40,155 0 0
TEXAS PAC LD TR SUB CTF PROP I T 882610108 12,395 14,370 SH   SOLE   14,370 0 0
TRUPANION INC COM 898202106 23,793 665,907 SH   SOLE   665,907 0 0
UBIQUITI NETWORKS INC COM 90347A100 5,920 59,880 SH   SOLE   59,880 0 0
VOLITIONRX LTD COM 928661107 4,699 1,814,152 SH   SOLE   1,814,152 0 0
WD-40 CO COM 929236107 12,305 71,500 SH   SOLE   71,500 0 0
XPO LOGISTICS INC COM 983793100 7,141 62,548 SH   SOLE   62,548 0 0