X0306 4 2017-09-25 0 0001631650 Aimmune Therapeutics, Inc. AIMT 0001222037 ADELMAN DANIEL C MD AIMMUNE THERAPEUTICS, INC. 8000 MARINA BOULEVARD, SUITE 300 BRISBANE CA 94005-1884 0 1 0 0 Chief Medical Officer Common Stock, $0.0001 par value 2017-09-25 4 M 0 10000 11.45 A 10000 D Common Stock, $0.0001 par value 2017-09-25 4 S 0 10000 25.00 D 0 D Stock Option (right to buy) 11.45 2017-09-25 4 M 0 10000 0.00 D 2026-06-24 Common Stock 10000 240000 D The sale reported in the Form 4 was effected pursuant to a Rule 10b5 1 trading plan adopted by the Reporting Person. The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on June 16, 2017 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued service relationship with the Issuer on each such vesting date. /s/ Douglas T. Sheehy, as Attorney-in-Fact for Daniel C. Adelman 2017-09-27