X0306 4 2017-05-25 0 0001631650 Aimmune Therapeutics, Inc. AIMT 0001253886 ENRIGHT PATRICK G C/O LONGITUDE CAPITAL PARTNERS II, LLC 800 EL CAMINO REAL, SUITE 220 MENLO PARK CA 94025 1 0 0 0 Common Stock, $0.0001 par value 6013134 I By: Longitude Venture Partners II, L.P. Common Stock, $0.0001 par value 7276 D Stock Option (right to buy) 18.26 2017-05-25 4 A 0 17500 0.00 A 2027-05-25 Common Stock 17500 17500 D The shares are held by Longitude Venture Partners II, L.P. ("Longitude Venture II"). Longitude Capital Partners II, LLC ("Longitude Capital II") is the general partner of Longitude Venture II and may be deemed to have sole voting, investment and dispositive power over the shares held by Longitude Venture II. Patrick G. Enright is a managing member of Longitude Capital II and in his capacity as such may be deemed to exercise shared voting and investment power over the shares held by Longitude Venture II. Mr. Enright disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein. The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of (i) the first anniversary of the grant date or (ii) the date of the 2018 Annual Meeting of the Issuer's stockholders, assuming continuous service as a director until such vesting date. /s/ Douglas T. Sheehy, as Attorney-in-Fact for Patrick G. Enright 2017-05-30