X0306 4 2016-02-26 0 0001631650 Aimmune Therapeutics, Inc. AIMT 0001344153 Knapp Jeffrey H C/O AIMMUNE THERAPEUTICS, INC. 8000 MARINA BOULEVARD, SUITE 300 BRISBANE CA 94005-1884 0 1 0 0 Chief Operating Officer Common Stock, $0.0001 par value 2016-02-26 4 A 0 5000 0.00 A 5000 D Stock Option (right to buy) 16.93 2016-02-26 4 A 0 250000 0.00 A 2026-02-26 Common Stock 250000 250000 D These shares represent restricted stock units ("RSUs") and will be settled in common stock upon vesting. The RSUs vest in full on February 1, 2017. The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on February 1, 2017 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued service relationship with the Issuer on each such vesting date. /s/ Warren L. DeSouza, as Attorney-in-Fact for Jeffrey H. Knapp 2016-02-26