144 0001657710 XXXXXXXX LIVE 0001631574 Wave Life Sciences Ltd. 001-37627 7 Straits View #12-00 Marina One East Tower Singapore U0 18936 65-6236 3388 PAUL BOLNO Officer ordinary shares Morgan Stanley Smith Barney LLC Executive Financial Services

1 New York Plaza 8th Floor New York NY 10004

10411 140027.95 187693059 02/09/2026 NASDAQ ordinary shares 02/08/2026 Restricted Stock Unit Vesting ISSUER N 10411 02/08/2026 Equity Compensation Y These sales were made pursuant to a provision in the reporting person's RSU agreement that requires automatic sales of shares to cover tax withholding obligations. 02/09/2026 Paul Bolno