0001104659-21-106048.txt : 20210816 0001104659-21-106048.hdr.sgml : 20210816 20210816131825 ACCESSION NUMBER: 0001104659-21-106048 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20210630 FILED AS OF DATE: 20210816 DATE AS OF CHANGE: 20210816 EFFECTIVENESS DATE: 20210816 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Sofinnova Investments, Inc. CENTRAL INDEX KEY: 0001631134 IRS NUMBER: 000000000 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-18774 FILM NUMBER: 211176343 BUSINESS ADDRESS: STREET 1: 3000 Sand Hill Road STREET 2: BUILDING 4-SUITE 250 CITY: Menlo Park STATE: CA ZIP: 94025 BUSINESS PHONE: 650.681.8428 MAIL ADDRESS: STREET 1: 3000 Sand Hill Road STREET 2: BUILDING 4-SUITE 250 CITY: Menlo Park STATE: CA ZIP: 94025 FORMER COMPANY: FORMER CONFORMED NAME: Sofinnova Ventures Inc DATE OF NAME CHANGE: 20150120 13F-HR 1 primary_doc.xml 13F-HR LIVE false false false 0001631134 XXXXXXXX 06-30-2021 06-30-2021 false Sofinnova Investments, Inc.

3000 Sand Hill Road Building 4-Suite 250 Menlo Park CA 94025

13F HOLDINGS REPORT 028-18774 Y Sofinnova Investments, Inc. is filing this Form 13F on behalf of itself and the general partner entities of the investment funds for which it serves as the investment adviser, Sofinnova Management VII, L.L.C., Sofinnova Management VIII, L.L.C., Sofinnova Management IX, L.L.C., Sofinnova Management X, L.L.C., and Sofinnova BioEquities GP LLC. Nathalie Auber 650-681-8428 /s/ Nathalie Auber Menlo Park CA 08-16-2021 0 67 1735092 INFORMATION TABLE 2 infotable.xml Aerovate Therapeutics, Inc. COMM 008064107 85811 3758686 SH SOLE 3758686 0 0 Akouos, Inc COMM 00973J101 19014 1515074 SH SOLE 1515074 0 0 Amarin Corp ADR 023111206 5127 1170584 SH SOLE 1170584 0 0 Ascendis Pharma A/S ADR 04351P101 68659 521923 SH SOLE 521923 0 0 Bolt Biotherapeutics, Inc. COMM 097702104 42584 2754437 SH SOLE 2754437 0 0 Checkmate Pharmaceuticals Inc COMM 162818108 21496 3606707 SH SOLE 3606707 0 0 Coherus BioSciences COMM 19249H103 6010 434555 SH SOLE 434555 0 0 Galera Therapeutics, Inc COMM 36338D108 30313 3083712 SH SOLE 3083712 0 0 Inozyme Pharma, Inc. COMM 45790W108 34562 2028308 SH SOLE 2028308 0 0 Karuna Therapeutics, Inc. COMM 48576A100 222559 1952441 SH SOLE 1952441 0 0 Natera COMM 632307104 352007 3100560 SH SOLE 3100560 0 0 Nextcure, Inc COMM 65343E108 21455 2671856 SH SOLE 2671856 0 0 Nucana Biomed Ltd ADR 67022C106 15512 5599999 SH SOLE 5599999 0 0 Nucana Biomed Ltd Ordinary Shares GB00BYWYV 6648 2400000 SH SOLE 2400000 0 0 ObsEva SA COMM H5861P103 14391 4749623 SH SOLE 4749623 0 0 PDS Biotechnology Corporation COMM 70465T107 1790 142635 SH SOLE 142635 0 0 Synlogic Inc. COMM 87166L100 2237 574972 SH SOLE 574972 0 0 Vera Therapeutics, Inc. CL A 92337R101 38650 2914776 SH SOLE 2914776 0 0 Y-mAbs Therapeutics, Inc COMM 984241109 74167 2194278 SH SOLE 2194278 0 0 ACADIA Pharmaceuticals Inc COMM 004225908 2439 100000 SH Call SOLE 100000 0 0 ARK ETF TR Genomic Rev ETF 00214Q952 23125 250000 SH Put SOLE 250000 0 0 Acceleron Pharma Inc COMM 00434H108 29319 233638 SH SOLE 233638 0 0 Agenus Inc COMM 00847G705 15207 2769900 SH SOLE 2769900 0 0 Agios Pharmaceuticals, Inc. COMM 00847X104 12071 219033 SH SOLE 219033 0 0 Align Technology Inc COMM 016255101 28774 47093 SH SOLE 47093 0 0 Aligos Therapeutics Inc COMM 01626L105 3344 164051 SH SOLE 164051 0 0 Amgen Inc COMM 031162100 9872 40500 SH SOLE 40500 0 0 AstraZeneca PLC ADR 046353108 57482 959632 SH SOLE 959632 0 0 BioCryst Pharmaceuticals Inc COMM 09058V103 2508 158609 SH SOLE 158609 0 0 Biogen Inc COMM 09062X103 38297 110600 SH SOLE 110600 0 0 CTI BioPharma Corp COMM 12648L601 429 171619 SH SOLE 171619 0 0 Celldex Therapeutics, Inc. COMM 15117B202 4505 134724 SH SOLE 134724 0 0 ChemoCentryx Inc COMM 16383L906 2879 215000 SH Call SOLE 215000 0 0 ChemoCentryx Inc COMM 16383L106 6235 465637 SH SOLE 465637 0 0 Cyteir Therapeutics, Inc. COMM 23284P103 5671 265000 SH SOLE 265000 0 0 Cytokinetics Inc COMM 23282W605 9525 481323 SH SOLE 481323 0 0 Dexcom Inc COMM 252131107 14395 33713 SH SOLE 33713 0 0 Exelixis Inc COMM 30161Q104 19672 1079681 SH SOLE 1079681 0 0 Fate Therapeutics Inc COMM 31189P102 4026 46386 SH SOLE 46386 0 0 FibroGen, Inc. COMM 31572Q958 5326 200000 SH Put SOLE 200000 0 0 Heron Therapeutics Inc COMM 427746102 22778 1467675 SH SOLE 1467675 0 0 Immatics NV COMM N44445109 5148 443370 SH SOLE 443370 0 0 Insmed Inc COMM 457669307 24025 844169 SH SOLE 844169 0 0 Insulet Corp COMM 45784P101 18804 68500 SH SOLE 68500 0 0 Intra-Cellular Therapies Inc COMM 46116X101 12783 313159 SH SOLE 313159 0 0 iShares TR iShares Biotech 464287956 53186 325000 SH Put SOLE 325000 0 0 Jounce Therapeutics Inc COMM 481116101 4248 624756 SH SOLE 624756 0 0 Kura Oncology Inc COMM 50127T109 9265 444372 SH SOLE 444372 0 0 MacroGenics Inc COMM 556099109 6299 234504 SH SOLE 234504 0 0 Marinus Pharmaceuticals Inc COMM 56854Q200 6210 346160 SH SOLE 346160 0 0 Mirati Therapeutics Inc COMM 60468T105 12686 78538 SH SOLE 78538 0 0 Mirum Pharmaceuticals Inc COMM 604749101 4486 259465 SH SOLE 259465 0 0 Neurocrine Biosciences, Inc. COMM 64125C109 19775 203200 SH SOLE 203200 0 0 Otonomy Inc COMM 68906L105 2790 1251256 SH SOLE 1251256 0 0 PTC Therapeutics Inc COMM 69366J200 24599 581940 SH SOLE 581940 0 0 Protagonist Therapeutics Inc COMM 74366E102 20155 449082 SH SOLE 449082 0 0 Reata Pharmaceuticals Inc COMM 75615P103 11266 79601 SH SOLE 79601 0 0 Regenxbio Inc COMM 75901B107 16618 427740 SH SOLE 427740 0 0 Replimune Group Inc COMM 76029N106 2753 71661 SH SOLE 71661 0 0 Sarepta Therapeutics, Inc. COMM 803607100 23205 298500 SH SOLE 298500 0 0 Savara Inc COMM 805111101 2173 1278424 SH SOLE 1278424 0 0 Sierra Oncology, Inc. COMM 82640U404 49 2500 SH SOLE 2500 0 0 TCR2 Therapeutics Inc COMM 87808K956 2292 139700 SH Put SOLE 139700 0 0 TCR2 Therapeutics Inc COMM 87808K106 4862 296282 SH SOLE 296282 0 0 Uniqure NV COMM N90064101 9989 324303 SH SOLE 324303 0 0 United Therapeutics Corp COMM 91307C102 38768 216085 SH SOLE 216085 0 0 Vertex Pharmaceuticals Inc COMM 92532F100 17787 88214 SH SOLE 88214 0 0