EX-10.31 6 s111877_ex10-31.htm EXHIBIT 10.31


Exhibit 10.31


Strategic Partnership Agreement


This Strategic Partnership Agreement is engaged by the following parties with the effective execution date on July 26, 2018.


Party A: Yen-Michael S. Hsu, M.D., Ph.D.
  Assistant Professor, Department of Pathology and Laboratory Medicine
  Director, Laboratory for Advanced Cellular Engineering (cGMP Cellular Therapy Facility)
  Weill Cornell Medical College of Cornell University
  Address: 530 East 70th Street, Room M-038
  New York, NY 10065, USA
  Phone: 212.746.2212


Party B: Avalon GloboCare Corp. and its subsidiaries
  Address: 4400 Route 9 South, Suite 3100
  Freehold, NJ 07728, USA
  Phone: 732.780.4400



This Agreement aims to establish a strategic partnership between Party A and Party B to: 1) co-develop technologies and standardization procedures in cellular therapy, including (but not limited to) CAR-T, CAR-NK, endothelial cells, stem cells, and exosomes; and 2) establish a biomedical research training program, sponsored by Avalon GloboCare Corp. under the supervision and guidance of Dr. Yen-Michael S. Hsu at Weill Cornell Medicine, Department of Pathology and Laboratory Medicine, to support qualified trainees from Lu Daopei Medical Group and affiliated hospitals, which are Avalon GloboCare’s clinical bases in China; the scope of this education fund includes (but not limited to): (i) exchange of scientific knowledge in the area of cellular therapy, (ii) promote innovative translational research related to cellular therapy, and (iii) joint publications.



1)Party A and Party B will co-develop standardization procedures in procurement, storage, processing, clinical study protocols, and biobanking for cellular therapies, in accordance to Foundation of Accreditation for Cellular Therapy (FACT) and American Association of Blood Banks (AABB) standards, which will enable Party B to apply such design of laboratory infrastructure and clinical studies in China and the US. Specific co-development projects to be determined by both parties.


2)Party B will provide a gift of USD $400,000.00 (in allotments) annually to Party A to financially support the aforementioned co-development projects as well as the education program, extendable yearly after the first year of satisfactory operation under mutual agreement between Party A and Party B.





3)Party B will send scientist or clinician (one person yearly) to receive relevant training (3- to 6-month period) under Party A in the area of cellular therapy, with additional funding provided by Party B to support accommodation and other living expenses incurred by the trainee.


4)According to Weill Cornell institutional Intellectual Property policies, any invention, process, products, data, know-how or any other element, information, or actual or potential Intellectual Property arising out of and during the course of the performance of this Agreement shall be the sole and exclusive property of Weill Cornell Medical College. Subject to the terms and conditions set forth herein, Weill Cornell Medical College hereby may consider to grant Party B an exclusive, worldwide, non-transferable license to make, use and sell any and all products and/or systems manufactured pursuant to this Agreement. Relevant royalty to be determined and agreed upon by Weill Cornell and Party B.




Party A:   Party B:
/s/ Yen-Michael S. Hsu   /s/ David Jin
Yen-Michael S. Hsu, M.D., Ph.D.   David Jin, M.D., Ph.D.
Assistant Professor, Department of   CEO and President
Pathology and Laboratory Medicine   Avalon GloboCare Corp.
Director, Laboratory of Advanced    
Cellular Therapy    
Date: August 6, 2018   Date:  August 6, 2018