X0306 4 2019-06-28 0000926617 VERMILLION, INC. VRML 0001629151 Schuler Henri George 100 N. FIELD DRIVE SUITE 360 LAKE FOREST IL 60045 true Common Stock, par value $0.001 2019-03-08 5 G 0 520035 0 D 520033 I By Schuler GC 2010 Continuation Trust Common Stock, par value $0.001 2019-03-08 5 G 0 520033 0 D 0 I By Schuler GC 2010 Continuation Trust Common Stock, par value $0.001 2019-06-28 4 P 0 2250000 0.8 A 6047057 I By Tanya Eva Schuler Trust Common Stock, par value $0.001 2019-06-28 4 P 0 2250000 0.8 A 6046957 I By Therese Heidi Schuler Trust Common Stock, par value $0.001 2019-06-28 4 P 0 250000 0.8 A 1503177 I By Schuler Grandchildren LLC Common Stock, par value $0.001 141304 I By Seascape Partners L.P. Common Stock, par value $0.001 26000 I By spouse Warrants (Right to buy) 1.8 2019-02-07 5 G 0 182536 0 D 2017-08-17 2022-02-17 Common Stock 182536 182536 I By Schuler GC 2010 Continuation Trust Warrants (Right to buy) 1.8 2019-02-07 5 G 0 182536 0 D 2017-08-17 2022-02-17 Common Stock 182536 0 I By Schuler GC 2010 Continuation Trust Warrants (Right to buy) 1.8 2017-08-17 2022-02-17 Common Stock 365072 365072 I By Tanya Eva Schuler Trust Warrants (Right to buy) 1.8 2017-08-17 2022-02-17 Common Stock 365072 365072 I By Therese Heidi Schuler Trust These shares of Common Stock ("Shares") and warrants to acquire Shares ("Warrants") are directly owned by the Tanya Eva Schuler Trust. H. George Schuler is the sole trustee of the Tanya Eva Schuler Trust. These Shares and Warrants are directly owned by the Therese Heidi Schuler Trust. H. George Schuler is the sole trustee of the Therese Heidi Schuler Trust. These Shares and Warrants are directly owned by the Schuler GC 2010 Continuation Trust. H. George Schuler is the sole trustee of the Schuler GC 2010 Continuation Trust. These Shares are directly owned by the Schuler Grandchildren LLC. H. George Schuler is the manager of the Schuler Grandchildren LLC. These Shares are directly owned by Seascape Partners L.P., a family limited partnership. H. George Schuler is the manager of Seascape Partners L.P. The reporting persons disclaim beneficial ownership of these Shares and Warrants except to the extent of his or its pecuniary interest therein, and this report shall not be deemed an admission that he or it is the beneficial owner of the Shares or Warrants for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose. /s/ H. George Schuler 2019-07-02