Condensed Consolidated Statements of Stockholders' Equity (Unaudited) - USD ($) $ in Thousands	Total	Common Stock [Member]	Additional Paid-In Capital [Member]	Accumulated Other Comprehensive Income [Member]	Accumulated Deficit [Member]
Beginning Balance at Dec. 31, 2020	$ 416,157	$ 62	$ 1,402,262	$ 302	$ (986,469)
Beginning Balance, Shares at Dec. 31, 2020		61,898,090
Issuance of common stock upon exercise of stock options	1,110		1,110
Issuance of common stock upon exercise of stock options, Shares		47,763
Issuance of common stock upon vesting of restricted share units, net of shares withheld for employee taxes	(1,897)		(1,897)
Issuance of common stock upon vesting of restricted share units, net of shares withheld for employee taxes, Shares		229,087
Issuance of common stock pursuant to ESPP purchases	2,558		2,558
Issuance of common stock pursuant to ESPP purchases, Shares		65,110
Stock-based compensation	20,378		20,378
Other comprehensive income	(181)			(181)
Net loss	(74,930)				(74,930)
Ending Balance at Mar. 31, 2021	363,195	$ 62	1,424,411	121	(1,061,399)
Ending Balance, Shares at Mar. 31, 2021		62,240,050
Beginning Balance at Dec. 31, 2020	416,157	$ 62	1,402,262	302	(986,469)
Beginning Balance, Shares at Dec. 31, 2020		61,898,090
Other comprehensive income	0
Net loss	(144,522)
Ending Balance at Jun. 30, 2021	315,766	$ 62	1,446,393	302	(1,130,991)
Ending Balance, Shares at Jun. 30, 2021		62,379,118
Beginning Balance at Mar. 31, 2021	363,195	$ 62	1,424,411	121	(1,061,399)
Beginning Balance, Shares at Mar. 31, 2021		62,240,050
Issuance of common stock upon exercise of stock options	403		403
Issuance of common stock upon exercise of stock options, Shares		28,575
Issuance of common stock upon vesting of restricted share units, net of shares withheld for employee taxes	(65)		(65)
Issuance of common stock upon vesting of restricted share units, net of shares withheld for employee taxes, Shares		110,493
Stock-based compensation	21,644		21,644
Other comprehensive income	181			181
Net loss	(69,592)				(69,592)
Ending Balance at Jun. 30, 2021	315,766	$ 62	1,446,393	302	(1,130,991)
Ending Balance, Shares at Jun. 30, 2021		62,379,118
Beginning Balance at Dec. 31, 2021	196,410	$ 65	1,485,805	100	(1,289,560)
Beginning Balance, Shares at Dec. 31, 2021		64,636,641
Issuance of common stock upon exercise of stock options	324		324
Issuance of common stock upon exercise of stock options, Shares		21,653
Issuance of common stock upon vesting of restricted share units, net of shares withheld for employee taxes	(981)		(981)
Issuance of common stock upon vesting of restricted share units, net of shares withheld for employee taxes, Shares		308,118
Issuance of common stock pursuant to ESPP purchases	2,259		2,259
Issuance of common stock pursuant to ESPP purchases, Shares		89,050
Stock-based compensation	19,475		19,475
Other comprehensive income	(2,062)			(2,062)
Net loss	(81,423)				(81,423)
Ending Balance at Mar. 31, 2022	134,002	$ 65	1,506,882	(1,962)	(1,370,983)
Ending Balance, Shares at Mar. 31, 2022		65,055,462
Beginning Balance at Dec. 31, 2021	$ 196,410	$ 65	1,485,805	100	(1,289,560)
Beginning Balance, Shares at Dec. 31, 2021		64,636,641
Issuance of common stock upon exercise of stock options, Shares	36,668
Stock Issued During Period, Shares, New Issues	2,065,358
Other comprehensive income	$ (4,072)
Net loss	(163,893)
Ending Balance at Jun. 30, 2022	118,360	$ 67	1,575,719	(3,973)	(1,453,453)
Ending Balance, Shares at Jun. 30, 2022		67,272,761
Beginning Balance at Mar. 31, 2022	134,002	$ 65	1,506,882	(1,962)	(1,370,983)
Beginning Balance, Shares at Mar. 31, 2022		65,055,462
Issuance of common stock upon exercise of stock options	216		216
Issuance of common stock upon exercise of stock options, Shares		15,015
Issuance of common stock upon vesting of restricted share units, net of shares withheld for employee taxes	(114)		(114)
Issuance of common stock upon vesting of restricted share units, net of shares withheld for employee taxes, Shares		136,916
Stock Issued During Period, Shares, New Issues		2,065,368
Stock Issued During Period, Value, New Issues	48,495	$ 2	48,493
Stock-based compensation	20,242		20,242
Other comprehensive income	(2,011)			(2,011)
Net loss	(82,470)				(82,470)
Ending Balance at Jun. 30, 2022	$ 118,360	$ 67	$ 1,575,719	$ (3,973)	$ (1,453,453)
Ending Balance, Shares at Jun. 30, 2022		67,272,761