Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Revenues [Abstract]
Product sales, net	$ 71,550	$ 47,555	$ 126,710	$ 86,598
Costs and operating expenses:
Cost of sales	1,413	748	2,468	1,332
Research and development	64,775	51,784	117,608	102,641
Selling, general and administrative	81,088	61,093	155,622	120,059
Total costs and operating expenses	147,276	113,625	275,698	224,032
Loss from operations	(75,726)	(66,070)	(148,988)	(137,434)
Other income (expense):
Interest income	1,664	164	2,164	493
Interest expense	(8,402)	(3,677)	(16,607)	(7,366)
Other income (expense), net	186	21	(100)	(62)
Total other income (expense,), net	(6,552)	(3,492)	(14,543)	(6,935)
Loss before income taxes	(82,278)	(69,562)	(163,531)	(144,369)
Provision for income taxes	192	30	362	153
Net loss	(82,470)	(69,592)	(163,893)	(144,522)
Other comprehensive loss:
Net unrealized gain on marketable securities, net of tax	(1,711)	(78)	(3,626)	(259)
Cumulative translation adjustment	(300)	259	(446)	259
Total other comprehensive expense, net	(2,011)	181	(4,072)	0
Comprehensive loss	$ (84,481)	$ (69,411)	$ (167,965)	$ (144,522)
Basic net loss per common share	$ (1.26)	$ (1.12)	$ (2.51)	$ (2.32)
Diluted net loss per common share	$ (1.26)	$ (1.12)	$ (2.51)	$ (2.32)
Weighted-average number of shares used in computing basic net loss per common share	65,594,792	62,312,418	65,220,518	62,207,328
Weighted-average number of shares used in computing diluted net loss per common share	65,594,792	62,312,418	65,220,518	62,207,328