X0306 4 2021-09-09 0 0001629137 Global Blood Therapeutics, Inc. GBT 0001662426 Morrison Scott W C/O GLOBAL BLOOD THERAPEUTICS, INC. 181 OYSTER POINT BLVD. SOUTH SAN FRANCISCO CA 94080 1 0 0 0 Common Stock 2021-09-09 4 S 0 4800 30.2089 D 3037 D Represents the weighted average sale price of the shares sold ranging from $30.1800 to $30.2850 per share, inclusive. The Reporting Person will provide, upon request by the Issuer, a security holder of the Issuer, or the staff of the Securities and Exchange Commission, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. /s/ Miguel Carrillo, Attorney-in-Fact 2021-09-10