X0306 4 2020-06-01 0 0001629137 Global Blood Therapeutics, Inc. GBT 0001188919 LOVE TED W C/O GLOBAL BLOOD THERAPEUTICS, INC. 181 OYSTER POINT BOULEVARD SOUTH SAN FRANCISCO CA 94080 1 1 0 0 See Remarks Restricted Stock Units 2020-06-01 4 A 0 141400 0.00 A Common Stock 141400 141400 D Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of Issuer's Common Stock. The RSUs vest in installments conditioned upon the achievement, on or before June 30, 2024, of up to three specified market price thresholds of the Issuer, subject to the Reporting Person's continuous service with the Issuer through each vesting date. The RSUs are subject to accelerated vesting upon termination without cause or resignation for good reason after a change of control of the Issuer. Title: President and Chief Executive Officer /s/ Tricia Suvari, Attorney-in-Fact 2020-06-03