X0306 5 2016-12-31 0 0 0 0001629137 Global Blood Therapeutics, Inc. GBT 0001650131 Radovich Peter C/O GLOBAL BLOOD THERAPEUTICS, INC. 400 EAST JAMIE COURT, SUITE 101 SOUTH SAN FRANCISCO CA 94080 0 1 0 0 See Remarks Common Stock 12500 I By Trust Common Stock 2016-07-31 5 A 0 1185 15.20 A 2410 D Common Stock 2017-01-31 5 A 0 812 13.73 A 3222 D These shares were erroneously reported as being directly owned in the Reporting Person's original Form 4 filed by the Reporting Person. These shares are held by The Radovich Family Trust. The Reporting Person and his spouse are co-trustees of the trust and share voting and investment control. Shares acquired pursuant to the Issuer's 2015 Employee Stock Purchase Plan in transactions that were exempt under both Rule 16b-3(d) and Rule 16b-3(c). Senior Vice President, Operations /s/ Leslie Calhoun as Attorney-in-Fact for the Reporting Person 2017-02-14