X0206 3 2015-08-11 0 0001629137 Global Blood Therapeutics, Inc. GBT 0001650131 Radovich Peter C/O GLOBAL BLOOD THERAPEUTICS, INC. 400 EAST JAMIE COURT, SUITE 101 SOUTH SAN FRANCISCO CA 94080 0 1 0 0 See Remarks Stock Option (Right to Buy) 1.61 2025-01-20 Common Stock 80000 D Stock Option (Right to Buy) 3.40 2025-04-08 Common Stock 37142 D 25% of the shares subject to this option shall vest and become exercisable on November 17, 2015, and the remaining shares subject to this option shall vest and become exercisable in 12 equal quarterly installments thereafter. The shares subject to this option shall vest and become exercisable in 16 equal quarterly installments, with the first installment on July 9, 2015. VP, Program Leadership and Business Strategy Exhibit List: Exhibit 24.1 - Power of Attorney /s/ John Schembri, attorney-in-fact 2015-08-11