X0206 3 2015-08-11 0 0001629137 Global Blood Therapeutics, Inc. GBT 0001650126 Choi Jung C/O GLOBAL BLOOD THERAPEUTICS, INC. 400 EAST JAMIE COURT, SUITE 101 SOUTH SAN FRANCISCO CA 94080 0 1 0 0 See Remarks Common Stock 142857 D Stock Option (Right to Buy) 3.40 2025-04-08 Common Stock 77142 D These shares of Common stock are subject to the Issuer's right of repurchase, which lapses with respect to 25% of the shares on April 6, 2016 and in 12 equal quarterly installments thereafter. 25% of the shares subject to this option shall vest and become exercisable on April 6, 2016, and the remaining shares subject to this option shall vest and become exercisable in 12 equal quarterly installments thereafter. Chief Business and Strategy Officer Exhibit List: Exhibit 24.1 - Power of Attorney /s/ John Schembri, attorney-in-fact 2015-08-11