X0206 3 2015-08-11 0 0001629137 Global Blood Therapeutics, Inc. GBT 0001188919 LOVE TED W C/O GLOBAL BLOOD THERAPEUTICS, INC. 400 EAST JAMIE COURT, SUITE 101 SOUTH SAN FRANCISCO CA 94080 1 1 0 0 See Remarks Common Stock 21428 D Common Stock 714285 D Common Stock 201428 D Common Stock 99285 D Common Stock 99285 D These shares of Common Stock are subject to the Issuer's right or repurchase, which lapses at a rate of 25% on September 4, 2014 and in 12 equal quarterly installments thereafter. These shares of Common Stock are subject to the Issuer's right or repurchase, which lapses at a rate of 25% on June 9, 2015 and in 12 equal quarterly installments thereafter. These shares of Common stock are subject to the Issuer's right of repurchase, which lapses in 16 equal quarterly installments, with the first installment on July 9, 2015. These shares of Common stock are subject to the Issuer's right of repurchase, which lapses upon the achievement of specified clinical and regulatory milestones within a specified period of time. These shares of Common Stock are subject to the Issuer's right of repurchase, which lapses with respect to all of the underlying shares upon the achievement of specified market capitalization of the Issuer. Chief Executive Officer and President Exhibit List: Exhibit 24.1 - Power of Attorney /s/ John Schembri, attorney-in-fact 2015-08-11