Income Taxes - Schedule of Significant Components of Deferred Tax Assets for Federal and State Income Taxes (Details) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Deferred tax assets:
Federal and state net operating loss carryforward	$ 34,921	$ 14,286
Research and other credits	11,876	2,858
Intangibles	1,714	1,211
Reserves and accruals	1,802	690
Stock-based compensation	326	22
Start-up costs	160	174
Other	1,091	141
Total gross deferred tax assets	51,890	19,382
Less valuation allowance	(50,678)	(19,350)
Total deferred tax assets	1,212	32
Deferred tax liabilities:
Other intangibles	(3,260)	(3,260)
Property, plant and equipment	(1,212)	(32)
Total gross deferred tax liability	(4,472)	(3,292)
Net deferred tax liability	$ (3,260)	$ (3,260)