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Stockholders' Equity - Fair Value of Stock Options, Valuation Assumptions (Details)
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Employee Stock Option    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Expected volatility, minimum 68.00% 66.00%
Expected volatility, maximum 70.00% 85.00%
Risk-free interest rate, minimum 1.20% 1.30%
Risk-free interest rate, maximum 1.50% 1.90%
Expected dividend yield 0.00% 0.00%
Employee Stock Option | Minimum    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Expected term (in years) 5 years 6 months 5 years 9 months 18 days
Employee Stock Option | Maximum    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Expected term (in years) 6 years 1 month 6 days 6 years 1 month 6 days
Non Employee Stock Option    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Expected volatility, minimum 62.00% 69.00%
Expected volatility, maximum 73.00% 72.00%
Risk-free interest rate, minimum 1.30% 1.60%
Risk-free interest rate, maximum 2.30% 2.30%
Expected dividend yield 0.00% 0.00%
Non Employee Stock Option | Minimum    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Expected term (in years) 7 years 7 years 8 months 12 days
Non Employee Stock Option | Maximum    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Expected term (in years) 10 years 10 years