Note 5. Balance Sheet Components

Property and Equipment, Net

Property and equipment, net, consist of the following:

	December 31,			December 31,
	2016			2015
	(in thousands)
Furniture and office equipment	$	624		$	168
Computer equipment		77			67
Software		175			87
Leasehold improvements		11,568			64
Laboratory equipment		2,974			723
Manufacturing equipment		5,200			—
Construction in progress		25			2,063
Total property and equipment		20,643			3,172
Less accumulated depreciation and amortization		(1,707	)		(204	)
Property and equipment, net	$	18,936		$	2,968

Property and equipment depreciation expense for the year ended December 31, 2016, 2015 and 2014 was $1.6 million, $0.2 million and $35,000, respectively.

Accrued Liabilities

Accrued liabilities consist of the following as of December 31, 2016 and 2015:

	December 31,		December 31,
	2016		2015
	(in thousands)
Accrued payroll and related expenses	$	3,164	$	1,152
Accrued research and development expenses		6,169		2,682
Accrued professional services		386		740
Other		152		223
Total accrued liabilities	$	9,871	$	4,797

Facility Lease Obligations

Facility lease obligations consist of the following as of December 31, 2016 and 2015:

	December 31, 2016						December 31, 2015
	Long-term		Current		Total		Long-term		Current		Total
	(in thousands)
Deferred rent	$	1,777	$	265	$	2,042	$	383	$	137	$	520
Asset retirement obligation		709		—		709		136		—		136
	$	2,486	$	265	$	2,751	$	519	$	137	$	656