X0306 4 2019-12-05 0 0001628738 Audentes Therapeutics, Inc. BOLD 0001580111 Holles Natalie C. C/O AUDENTES THERAPEUTICS, INC. 600 CALIFORNIA STREET, 17TH FLOOR SAN FRANCISCO CA 94108 0 1 0 0 President and COO Common Stock 2019-12-05 4 F 0 505 59.21 D 54704 D Shares relinquished by the Reporting Person and cancelled by the Issuer in exchange for the Issuer's agreement to pay federal and state tax withholding obligations of the Reporting Person resulting from the vesting of restricted stock units. The Reporting Person did not sell or otherwise dispose of the shares for any reason other than to cover required taxes. /s/ Mark Meltz as attorney-in-fact for Natalie Holles 2019-12-09