Amount of expense for research and development. Includes, but is not limited to, cost for computer software product to be sold, leased, or otherwise marketed and writeoff of research and development assets acquired in transaction other than business combination or joint venture formation or both. Excludes write-down of intangible asset acquired in business combination or from joint venture formation or both, used in research and development activity.

Reference 1: http://www.xbrl.org/2003/role/exampleRef
-Topic 280
-SubTopic 10
-Name Accounting Standards Codification
-Section 55
-Paragraph 48
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482785/280-10-55-48

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
-Topic 985
-SubTopic 20
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481283/985-20-50-2

Reference 3: http://www.xbrl.org/2003/role/disclosureRef
-Topic 730
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 1
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482916/730-10-50-1

Reference 4: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 912
-SubTopic 730
-Name Accounting Standards Codification
-Section 25
-Paragraph 1
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479532/912-730-25-1

Name:	us-gaap_ResearchAndDevelopmentExpense
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

Related Party Transactions - Additional Information (Details)	12 Months Ended
	Dec. 31, 2024 USD ($)	Dec. 31, 2023 USD ($)	Dec. 31, 2022 USD ($)	Sep. 30, 2021 ft²	Aug. 31, 2021 ft²	Feb. 01, 2015 ft²
Related Party Transaction [Line Items]
Research and development	$ 19,385,000	$ 16,526,000	$ 24,468,000
Burlingame Lease
Related Party Transaction [Line Items]
Area of leased facility \| ft²				27,280		8,138
Equity Method Investee \| Sublease Agreement \| Burlingame Lease
Related Party Transaction [Line Items]
Area of leased facility \| ft²					7,585
Sublease income		100,000	600,000
ICON PLC \| Clinical Trial Support Agreement
Related Party Transaction [Line Items]
Research and development	$ 351,000	$ 254,000
ICON PLC \| Clinical Trial Support Agreement \| Burlingame Lease
Related Party Transaction [Line Items]
Research and development			$ 429,000