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License and Collaboration Agreements (Details) - USD ($)
1 Months Ended 12 Months Ended
Feb. 28, 2017
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2017
Dec. 31, 2015
Research and Development Arrangement, Contract to Perform for Others [Line Items]            
Initial cash payment   $ 19,385,000 $ 16,526,000 $ 24,468,000    
Annual licensing fee   25,000        
Licensing Agreement | Scripps Research Institute            
Research and Development Arrangement, Contract to Perform for Others [Line Items]            
Initial cash payment           $ 10,000
Annual licensing fee   25,000        
Milestone payments   0        
Aggregate potential milestone payments   $ 2,500,000        
Early termination notice period   90 days        
Licensing Agreement | Vernalis (R&D) Limited            
Research and Development Arrangement, Contract to Perform for Others [Line Items]            
Initial cash payment           $ 1,000,000
Milestone payments $ 3,000,000 $ 0        
Aggregate potential milestone payments   $ 220,000,000        
Early termination notice period   90 days        
Licensing Agreement | Monash University            
Research and Development Arrangement, Contract to Perform for Others [Line Items]            
Initial cash payment         $ 275,000  
Milestone payments   $ 0        
Aggregate potential milestone payments   $ 45,100,000        
Early termination notice period   30 days