Facility Leases (Tables)

12 Months Ended

Dec. 31, 2024

Burlingame Lease

Lessee, Lease, Description [Line Items]

Schedule of components of lease expense

		Year Ended
	Statements of operations and	December 31,
	comprehensive loss location	2024		2023		2022
Costs of operating lease
Operating lease costs	Research and development, General and administrative	$	1,273	$	1,224	$	1,051
Costs of non-lease components (previously common area maintenance)	Research and development, General and administrative		471		420		351
Total operating lease cost		$	1,744	$	1,644	$	1,402
Other Information
Operating cash flows used for operating lease		$	1,892	$	1,839	$	1,695
Remaining lease term			0.1 years		1.1 years		2.1 years
Discount rate			8.0%		8.0%		8.0%

Schedule of Minimum rental commitments

As of December 31, 2023, minimum rental commitments under the Burlingame Lease were as follows (in thousands):

Year Ended December 31 (in thousands)
2024	$	1,434
Total lease payments		1,434
Less: imputed interest		(60)
Total	$	1,374

South San Francisco Lease

Lessee, Lease, Description [Line Items]

Schedule of components of lease expense

		Year Ended
	Statements of operations and	December 31,
	comprehensive loss location	2024
Costs of operating lease
Operating lease costs	Research and development, General and administrative	$	46
Costs of non-lease components (previously common area maintenance)	Research and development, General and administrative		—
Total operating lease cost		$	46
Other Information
Operating cash flows used for operating lease		$	153
Remaining lease term			3 years
Discount rate			11.7%

Schedule of Minimum rental commitments

As of December 31, 2024, minimum rental commitments under the South San Francisco Lease were as follows (in thousands):

Year Ended December 31 (in thousands)
2025	$	305
2026		486
2027	$	566
Total lease payments		1,357
Less: imputed interest		(235)
Total	$	1,122