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License and Collaboration Agreements (Details) - USD ($)
12 Months Ended
Dec. 31, 2022
Feb. 28, 2017
Dec. 31, 2015
Feb. 28, 2015
Monash License        
License and Collaboration Agreements        
Minimum annual fee $ 25,000      
Period of written notice to terminate 30 days      
Monash License | Maximum        
License and Collaboration Agreements        
Aggregate potential milestone payments $ 45,100,000      
Monash License | Research and development        
License and Collaboration Agreements        
One-time cash payment 275,000      
Licensing Agreement | Scripps Research Institute        
License and Collaboration Agreements        
Minimum annual fee     $ 25,000  
Aggregate potential milestone payments 2,500,000      
Milestone payments made $ 0      
Period of written notice to terminate 90 days      
Licensing Agreement | Scripps Research Institute | Research and development        
License and Collaboration Agreements        
One-time cash payment     $ 10,000  
Licensing Agreement | Vernalis (R&D) Limited        
License and Collaboration Agreements        
Milestone payments made   $ 3,000,000.0    
Period of written notice to terminate 90 days      
Licensing Agreement | Vernalis (R&D) Limited | Minimum        
License and Collaboration Agreements        
Aggregate potential milestone payments $ 220,000,000      
Licensing Agreement | Vernalis (R&D) Limited | Research and development        
License and Collaboration Agreements        
One-time cash payment       $ 1,000,000.0