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Equity Method Investment (Details) - USD ($)
$ in Thousands
1 Months Ended 12 Months Ended
Oct. 31, 2020
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Schedule of Equity Method Investments [Line Items]        
Gain on deconsolidation of Angel Pharmaceuticals       $ 37,459
Loss from equity method investment   $ 10,005 $ 4,831 234
Net loss   $ (41,307) (43,241) (5,995)
Angel Pharmaceuticals        
Schedule of Equity Method Investments [Line Items]        
Ownership interest (as percent) 53.20% 49.70%    
Exclusive grant back period 7 years      
Equity reserved (as percent)   7.00%    
Investment in Angel, fair value $ 37,500      
Gain on deconsolidation of Angel Pharmaceuticals $ 37,500      
Loss from equity method investment   $ 10,000 4,800 200
Net loss   (11,846) (5,697) (274)
Share of loss from investments accounted for using the equity method   $ (10,005) $ (4,831) $ (234)