License and Collaboration Agreements (Details)	9 Months Ended
	Sep. 30, 2022 USD ($)	May 31, 2017 USD ($)	Feb. 28, 2017 USD ($)	Dec. 31, 2015 USD ($)	Feb. 28, 2015 USD ($)
Monash License
License and Collaboration Agreements
Minimum annual fee	$ 25,000
Aggregate potential milestone payments	$ 45,100,000
Period of written notice to terminate	30 days
Monash License | Research and development
License and Collaboration Agreements
One-time cash payment	$ 275,000
Licensing Agreement | Scripps Research Institute
License and Collaboration Agreements
Minimum annual fee				$ 25,000
Aggregate potential milestone payments	$ 2,500,000
Period of written notice to terminate	90 days
Licensing Agreement | Scripps Research Institute | Research and development
License and Collaboration Agreements
One-time cash payment				$ 10,000
Licensing Agreement | Vernalis (R&D) Limited
License and Collaboration Agreements
Milestone payments made			$ 3,000,000.0
Period of written notice to terminate	90 days
Licensing Agreement | Vernalis (R&D) Limited | Minimum
License and Collaboration Agreements
Aggregate potential milestone payments	$ 220,000,000
Licensing Agreement | Vernalis (R&D) Limited | Research and development
License and Collaboration Agreements
One-time cash payment					$ 1,000,000.0
Clinical Trial Collaboration Agreement | Genentech
License and Collaboration Agreements
Number of patients enrollment completed		16