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STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2020
Mar. 31, 2019
Cash flows from operating activities    
Net loss $ (12,935) $ (11,643)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 184 186
Accretion related to marketable securities (64) (170)
Stock-based compensation 1,845 1,953
Changes in operating assets and liabilities:    
Prepaid and other current assets 226 (205)
Operating lease right-of-use asset 164 146
Other assets   (51)
Accounts payable 908 266
Accrued and other liabilities 530 714
Operating lease liability (211) (186)
Net cash used in operating activities (9,353) (8,990)
Cash flows from investing activities    
Purchases of marketable securities (11,411) (29,903)
Sales of marketable securities 1,009  
Maturities of marketable securities 38,099 38,688
Purchases of property and equipment   (16)
Net cash provided by investing activities 27,697 8,769
Cash flows from financing activities    
Proceeds from exercise of common stock options   1
Net cash provided by financing activities   1
Net increase (decrease) in cash and cash equivalents 18,344 (220)
Cash and cash equivalents at beginning of the period 5,154 39,196
Cash and cash equivalents at end of the period $ 23,498 38,976
Supplemental disclosures of cash flow information    
Purchases of property and equipment incurred but not paid   $ 16