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Net Loss per Share - Anti-Dilutive Securities (Details) - shares
3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Excluded from the calculation of diluted net loss per share, due to anti-dilutive effect    
Shares of common stock equivalents 4,067,998 3,245,075
Common stock subject to repurchase    
Excluded from the calculation of diluted net loss per share, due to anti-dilutive effect    
Shares of common stock equivalents 27,073 246,079
Outstanding options    
Excluded from the calculation of diluted net loss per share, due to anti-dilutive effect    
Shares of common stock equivalents 4,040,925 2,998,996