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Income Taxes - Schedule of Effective Income Tax Rate Reconciliation (Details)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Income Tax Disclosure [Abstract]      
U.S. statutory tax rate 21.00% 21.00% 21.00%
State taxes, net of federal benefit 5.58% 4.91% 3.25%
Foreign tax rate differentials 0.83% 0.66% 0.33%
Research and development credit 2.65% 4.97% 3.24%
Purchase price accounting 0.35% 0.00% 0.00%
Stock-based compensation 26.29% 16.97% 0.38%
162(m) addback (15.65%) 0.00% 0.00%
Permanent differences, other (0.92%) (8.17%) (3.77%)
Change in valuation allowance (40.09%) (40.41%) (24.50%)
Effective tax rate 0.04% (0.07%) (0.07%)