<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2021-07-02</periodOfReport>

    <notSubjectToSection16>true</notSubjectToSection16>

    <issuer>
        <issuerCik>0001626450</issuerCik>
        <issuerName>BigCommerce Holdings, Inc.</issuerName>
        <issuerTradingSymbol>BIGC</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001819272</rptOwnerCik>
            <rptOwnerName>Vaillancourt Paul</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>11305 FOUR POINTS DRIVE</rptOwnerStreet1>
            <rptOwnerStreet2>BUILDING II, THIRD FLOOR</rptOwnerStreet2>
            <rptOwnerCity>AUSTIN</rptOwnerCity>
            <rptOwnerState>TX</rptOwnerState>
            <rptOwnerZipCode>78726</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>false</isDirector>
            <isOfficer>true</isOfficer>
            <isTenPercentOwner>false</isTenPercentOwner>
            <isOther>false</isOther>
            <officerTitle>Chief Services Officer</officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable></nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes></footnotes>

    <remarks>The reporting person retired as BigCommerce Holdings, Inc. chief services officer effective July 2, 2021. As a result, the reporting person is no longer subject to Section 16 in connection with his transactions in the equity securities of BigCommerce Holdings, Inc. and therefore will no longer report any such transactions on Form 4 or Form 5.</remarks>

    <ownerSignature>
        <signatureName>/s /Jeff Mengoli, Attorney-in-Fact for Paul Vaillancourt</signatureName>
        <signatureDate>2021-07-12</signatureDate>
    </ownerSignature>
</ownershipDocument>
